Diguanosine 5′-triphosphate (lithium)

• UNSPSC Description:

  Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphates. Diguanosine 5′-triphosphate lithium also is a virus-specific oligonucleotide. Diguanosine 5′-triphosphate lithium is needed for the synthesis of RNA during the transcription process[1][2].

• Target Antigen:

  DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/diguanosine-5-triphosphate-lithium.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@@H](O)[C@H](N(C=N2)C(NC(N)=N3)=C2C3=O)O[C@@H]1COP(OP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C=NC6=C5NC(N)=NC6=O)O4)(O)=O)(O)=O)(O)=O.[x].[Li]

• References & Citations:

  [1]M Yamakawa, et al. Priming of reovirus transcription by GppppG and formation of CpG(5')GpC. Proc Natl Acad Sci U S A. 1982 Oct;79(20):6142-6. |[2]Emmanuel Klein, et al. Synthesis of enzymatically and chemically non-hydrolyzable analogues of dinucleoside triphosphates Ap(3)A and Gp(3)G. J Org Chem. 2002 Jan 11;67(1):146-53.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported