BVDU 5′-Triphosphate
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804-HY-W747737
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

BVDU 5′-Triphosphate
- CAS Number: 77222-61-8
- UNSPSC Description: BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.
- Target Antigen: DNA/RNA Synthesis; HSV
- Type: Reference compound
- Related Pathways: Anti-infection;Cell Cycle/DNA Damage
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/bvdu-5-triphosphate.html
- Solubility: 10 mM in DMSO
- Smiles: OP(OP(OP(O)(OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(/C=C/Br)=C2)=O)=O)O1)=O)(O)=O)(O)=O
- Molecular Weight: 573.08
- References & Citations: [1]De Clercq E. Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. Biochem Pharmacol. 2004 Dec 15;68(12):2301-15.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported