BVDU 5′-Triphosphate

CAT:

804-HY-W747737

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CAS Number: 77222-61-8
UNSPSC Description: BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.
Target Antigen: DNA/RNA Synthesis; HSV
Type: Reference compound
Related Pathways: Anti-infection;Cell Cycle/DNA Damage
Applications: COVID-19-anti-virus
Field of Research: Infection
Assay Protocol: https://www.medchemexpress.com/bvdu-5-triphosphate.html
Solubility: 10 mM in DMSO
Smiles: OP(OP(OP(O)(OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(/C=C/Br)=C2)=O)=O)O1)=O)(O)=O)(O)=O
Molecular Weight: 573.08
References & Citations: [1]De Clercq E. Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. Biochem Pharmacol. 2004 Dec 15;68(12):2301-15.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-W747737	BVDU 5′-Triphosphate
HY-W747737A-02	BVDU 5′-Triphosphate (ammonium)
HY-W747737A-01	BVDU 5′-Triphosphate (ammonium)
HY-148653-01	(+)-C-BVDU
HY-148653-02	(+)-C-BVDU
HY-147338	5-Methylcytidine 5′-triphosphate
HY-155868	5-Azacytidine 5′-triphosphate
HY-141567	Pseudouridine 5'-triphosphate
HY-164840	Clofarabine-5'-triphosphate
HY-125818-01	Cytidine-5'-triphosphate

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