Diguanosine 5′-triphosphate

Diguanosine 5′-triphosphate

• CAS Number: 6674-45-9
• UNSPSC Description: Diguanosine 5′-triphosphate (Gp3G) is a dinucleoside triphosphates. Diguanosine 5′-triphosphate also is a virus-specific oligonucleotide. Diguanosine 5′-triphosphate is needed for the synthesis of RNA during the transcription process[1][2].
• Target Antigen: DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: COVID-19-anti-virus
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/diguanosine-5-triphosphate.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@@H](O)[C@H](N(C=N2)C(NC(N)=N3)=C2C3=O)O[C@@H]1COP(OP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C=NC6=C5NC(N)=NC6=O)O4)(O)=O)(O)=O)(O)=O
• Molecular Weight: 788.41
• References & Citations: [1]M Yamakawa, et al. Priming of reovirus transcription by GppppG and formation of CpG(5')GpC. Proc Natl Acad Sci U S A. 1982 Oct;79(20):6142-6.|[2]Emmanuel Klein, et al. Synthesis of enzymatically and chemically non-hydrolyzable analogues of dinucleoside triphosphates Ap(3)A and Gp(3)G. J Org Chem. 2002 Jan 11;67(1):146-53.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported