Xanthosine-5'-Triphosphate

• Description :

  Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide, is produced by deamination of purine bases. Xanthosine-5'-Triphosphate is a substrate of inosine triphosphate pyrophosphatase (ITPase) [1].

• CAS Number :

  [6253-56-1]

• Product Name Alternative :

  5'-XTP

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog; Phosphatase

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/xanthosine-5-triphosphate.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C(N=C1)=C(N2)N1[C@@H]3O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)[C@H]3O)NC2=O

• Molecular Formula :

  C10H15N4O15P3

• Molecular Weight :

  524.17

• References & Citations :

  [1]Davies O, et, al. Characterisation of multiple substrate-specific (d) ITP/ (d) XTPase and modelling of deaminated purine nucleotide metabolism. BMB Rep. 2012 Apr;45 (4) :259-64.|[2]Lin S, et al. Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene. J Biol Chem. 2001 Jun 1;276 (22) :18695-701.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported