Deoxythymidine-5'-triphosphate-13C10,15N2 (dilithium)

• CAS Number:

  2483830-18-6

• UNSPSC Description:

  Deoxythymidine-5'-triphosphate-13C10,15N2 (dTTP-13C10,15N2) dilithium is 13C and 15N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.

• Target Antigen:

  DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Infection

• Assay Protocol:

  https://www.medchemexpress.com/deoxythymidine-5-triphosphate-13c10-15n2-dilithium.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=[13C]([15N]1[13C@H]2[13CH2][13C@H](O)[13C@@H]([13CH2]OP(O)(OP(OP(O)(O[Li])=O)(O[Li])=O)=O)O2)[15NH][13C]([13C]([13CH3])=[13CH]1)=O

• Molecular Weight:

  505.95

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5(2):191-202.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported