Deoxythymidine-5'-triphosphate-15N2 (dilithium)

Deoxythymidine-5'-triphosphate-15N2 (dilithium)

• UNSPSC Description: Deoxythymidine-5'-triphosphate-15N2 (dTTP-15N2) dilithium is 15N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
• Target Antigen: DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog
• Type: Isotope-Labeled Compounds
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others
• Applications: COVID-19-anti-virus
• Field of Research: Cancer; Infection
• Assay Protocol: https://www.medchemexpress.com/deoxythymidine-5-triphosphate-15n2-dilithium.html
• Purity: 99.0
• Solubility: 10 mM in DMSO
• Smiles: O=C([15N]1[C@H]2C[C@H](O)[C@@H](COP(O)(OP(OP(O)(O[Li])=O)(O[Li])=O)=O)O2)[15NH]C(C(C)=C1)=O
• Molecular Weight: 496.02
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5(2):191-202.
• Shipping Conditions: Blue Ice
• Storage Conditions: Solution, -20°C, 2 years
• Clinical Information: No Development Reported