NOS-IN-1

• Description :

  NOS-IN-1 is a potent and orally active NO synthase (NOS) isoforms inhibitor with IC50s of 0.1 μM, 1.1 μM, and 0.2 μM for human iNOS (hiNOS), heNOS and hnNOS, respectively[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  NO Synthase

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/nos-in-1.html

• Purity :

  98.18

• Solubility :

  10 mM in DMSO

• Smiles :

  NC1=NCCC(C)C1.CC(O)=O

• Molecular Formula :

  C8H16N2O2

• Molecular Weight :

  172.22

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]R K Webber, et al. Substituted 2-iminopiperidines as inhibitors of human nitric oxide synthase isoforms. J Med Chem. 1998 Jan 1;41 (1) :96-101.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  INOS; nNOS

• CAS Number :

  [165383-72-2]