NOS-IN-3

• Description :

  NOS-IN-3 (Compound 9a) is a potent, selective, imidamide derived NOS inhibitor with an IC50 against iNOS of 4.6 μM, without inhibiting eNOS. NOS-IN-3 has little toxicity and can be studied in the research of inducible isoform involved diseases, such as septic shock[1].

• UNSPSC :

  12352005

• Target :

  NO Synthase

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/nos-in-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(NCCC(C1=CC=CN=C1)O)=N

• Molecular Formula :

  C10H15N3O

• Molecular Weight :

  193.25

• References & Citations :

  [1]Fabio Arias, et al. Bioactive imidamide-based compounds targeted against nitric oxide synthase. Bioorg Chem. 2022 Feb 2;120:105637.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  INOS; nNOS

• CAS Number :

  [2761725-68-0]