NOS-IN-3

CAT: 0804-HY-115917Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-115917Size:1 Each
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Description
NOS-IN-3 (Compound 9a) is a potent, selective, imidamide derived NOS inhibitor with an IC50 against iNOS of 4.6 μM, without inhibiting eNOS. NOS-IN-3 has little toxicity and can be studied in the research of inducible isoform involved diseases, such as septic shock[1].
CAS Number
[2761725-68-0]
UNSPSC
12352005
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nos-in-3.html
Solubility
10 mM in DMSO
Smiles
CC(NCCC(C1=CC=CN=C1)O)=N
Molecular Formula
C10H15N3O
Molecular Weight
193.25
References & Citations
[1]Fabio Arias, et al. Bioactive imidamide-based compounds targeted against nitric oxide synthase. Bioorg Chem. 2022 Feb 2;120:105637.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
INOS; nNOS

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