NOS-IN-2

CAT:

804-HY-115916

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1 Each

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Description :
NOS-IN-2 (Compound 4i) is a potent, selective, imidamide derived NOS inhibitor with an IC50 against iNOS of 20 μM, without inhibiting eNOS. NOS-IN-2 has little toxicity and can be used for studying inflammatory disorders[1].
UNSPSC :
12352005
Target :
NO Synthase
Type :
Reference compound
Related Pathways :
Immunology/Inflammation
Applications :
COVID-19-immunoregulation
Field of Research :
Inflammation/Immunology
Assay Protocol :
https://www.medchemexpress.com/nos-in-2.html
Solubility :
10 mM in DMSO
Smiles :
COC1=CC=C(C(C(CCNC(C2=CC=C(C=C2)C(F)(F)F)=N)O)=C1)N
Molecular Formula :
C18H20F3N3O2
Molecular Weight :
367.37
References & Citations :
[1]Fabio Arias, et al. Synthesis, bioevaluation and docking studies of new imidamide derivatives as nitric oxide synthase inhibitors. Bioorg Med Chem. 2021 Aug 15;44:116294.
Shipping Conditions :
Room temperature
Scientific Category :
Reference compound1
Clinical Information :
No Development Reported
Isoform :
INOS; nNOS
CAS Number :
[2766146-79-4]

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