WL 47 dimer

CAT: 0804-HY-P10332Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P10332Size:1 Each
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Description
WL 47 dimer (ligand 1) is a caveolin-1 (CAV-1) ligand with high affinity, selectivity and oligomer dissociation activity. WL 47 dimer simultaneously occupies two binding sites of CAV-1, inducing the dissociation of oligomers. WL 47 dimer has 7500-fold improved affinity compared to its T20 parent ligand and an 80% decrease in sequence length. WL 47 dimer can be used to permit targeted study of CAV-1 function[1].
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/wl-47-dimer.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CSSC[C@H](N)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCSC)=O)CC1=CNC2=CC=CC=C12)=O)CO)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCSC)=O)CC3=CNC4=CC=CC=C34)=O)CO
Molecular Formula
C80H130N24O18S4
Molecular Weight
1844.30
References & Citations
[1]Gilliam A J H, et al. Affinity-guided design of caveolin-1 ligands for deoligomerization[J]. Journal of medicinal chemistry, 2016, 59 (8) : 4019-4025.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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