Fluticasone dimer impurity

• Description:

  Fluticasone dimer impurity is a dimeric impurity of Fluticasone Propionate[1]. Fluticasone propionate is a corticosteroid with comparatively high receptor affinity and topical activity[2].

• UNSPSC:

  12352100

• Hazard Statement:

  H302-H312-H315-H319-H332

• Target:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/fluticasone-dimer-impurity.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@H](C2)O)([C@@]4(C([C@H](C3)F)=CC(C=C4)=O)C)F)([H])C[C@H]1C)C)O)O[C@]5([C@@]6([C@@]([C@@]7([H])[C@]([C@H](C6)O)([C@@]8(C([C@H](C7)F)=CC(C=C8)=O)C)F)([H])C[C@H]5C)C)C(SCF)=O

• Molecular Formula:

  C43H51F5O8S

• Molecular Weight:

  822.92

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501

• References & Citations:

  [1]The synthetic method of fluticasone propionate impurity. CN110105419A.|[2]Jarvis B, et al. Inhaled fluticasone propionate: a review of its therapeutic efficacy at dosages < or = 500 microg/day in adults and adolescents with mild to moderate asthma. Drugs. 1999;57 (5) :769-803.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  220589-37-7