20α,22R-Dihydroxycholesterol

20α,22R-Dihydroxycholesterol

• CAS Number: 596-94-1
• UNSPSC Description: 20α,22R-Dihydroxycholesterol is an endogenous metabolic intermediate. 20α,22R-Dihydroxycholesterol involved in the biosynthesis of cholesterol to steroid hormones[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/20α-22r-dihydroxycholesterol.html
• Solubility: 10 mM in DMSO
• Smiles: C[C@@]1([C@@]2([H])[C@@](C)(O)[C@H](O)CCC(C)C)[C@](CC2)([H])[C@@](CC=C(C3)[C@@]4(CC[C@@H]3O)C)([H])[C@]4([H])CC1
• Molecular Weight: 418.65
• References & Citations: [1]Mast N, et, al. Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem. 2011 Feb 18;286(7):5607-13.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported