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Nek2-IN-4

CAT: 0804-HY-137046Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137046Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has the potential for the research of pancreatic cancer[1].
CAS Number
2225902-88-3
UNSPSC
12352005
Target
NEKs
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nek2-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(O[C@H](C2=CC=CC=C2C(F)(F)F)C)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)S1)N
Molecular Formula
C28H27F3N6O2S
Molecular Weight
568.61
References & Citations
[1]Hong-Yu Li, et al. Small molecule inhibitors of nek2 and uses thereof. WO2018081719A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NEK2

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