Nek2-IN-4

Nek2-IN-4

• CAS Number: 2225902-88-3
• UNSPSC Description: Nek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has the potential for the research of pancreatic cancer[1].
• Target Antigen: NEKs
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/nek2-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=C(O[C@H](C2=CC=CC=C2C(F)(F)F)C)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)S1)N
• Molecular Weight: 568.61
• References & Citations: [1]Hong-Yu Li, et al. Small molecule inhibitors of nek2 and uses thereof. WO2018081719A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported