Nek2/Hec1-IN-2

Nek2/Hec1-IN-2

• CAS Number: 544416-00-4
• UNSPSC Description: Nek2/Hec1-IN-2 (Compound 14) is an inhibitor of Nek2/Hec1. Nek2/Hec1-IN-2 inhibits cancer cell proliferation with IC50 >25 μM[1].
• Target Antigen: NEKs
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/nek2-hec1-in-2.html
• Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(C1=NC=CN=C1)NC2=NC(C3=C(C)C=C(C)C=C3)=CS2
• Molecular Weight: 310.37
• References & Citations: [1]Qiu XL, et al. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J Med Chem. 2009 Mar 26;52(6):1757-67.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported