Nek2/Hec1-IN-1

Nek2/Hec1-IN-1

• CAS Number: 560103-80-2
• UNSPSC Description: N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide is a derivative of INH1 with anticancer activity. It is cytotoxic to MDA-MB-231, MDA-MB-488, HeLa, and K562 cells (IC50s=1.1, 3.4, 1.6, and 1.2 μM, respectively).
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/nek2-hec1-in-1.html
• Smiles: O=C(C1=CC=NC=C1)NC2=NC(C3=CC=C(C)C=C3C)=CS2
• Molecular Weight: 309.39
• References & Citations: [1]Qiu, et al. Synthesis and biological evaluation of a series of novel inhibitor of Nek2/Hec1 analogues. J. Med. Chem. 52(6), 1757-1767 (2009).
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported