K-41

• Description:

  K-41 is an orally active antibiotic. K-41 can be obtained from Streptomyces hygroscopicus. K-41 has antibacterial and antiplasmodial activity[1][2].

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial; Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/k-41.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@H] ([C@H]1OC) [C@] (O[C@@H] (C2) C[C@H] (O[C@]3 (O) [C@@H] (O) C (O) =O) [C@@] (C) ([C@H] ([C@@H]3C) OC) OC) ([C@@H] ([C@@H]2OC) C) O[C@@]1 ([C@]4 ([H]) O[C@@] ([C@]5 ([H]) O[C@] ([C@] (O[C@@]6 (O) C) ([H]) [C@H] ([C@@H] ([C@H]6C) O[C@@H] (CC[C@@H]7OC) O[C@@H]7C) C) ([H]) CC5) ([H]) CC4) C

• Molecular Formula:

  C48H82O18

• Molecular Weight:

  947.15

• References & Citations:

  [1]Otoguro K, et al. In vitro and in vivo antimalarial activities of the monoglycoside polyether antibiotic, K-41 against drug resistant strains of Plasmodia. J Antibiot (Tokyo) . 2002 Sep;55 (9) :832-4.|[2]Tsuji N, et al. Two new antibiotics, A-218 and K-41. Isolation and characterization. J Antibiot (Tokyo) . 1976 Jan;29 (1) :10-4.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  53026-37-2