STAT3-IN-41

• Description :

  STAT3-IN-41 (Compound 16) is a prodrug of compound 1. STAT3-IN-41 slowly releases compound 1 inhibiting STAT3 signaling pathway. STAT3-IN-41 shows antitumor activity against lung cancer, hepatocellular carcinoma and pancreatic cancer[1].

• UNSPSC :

  12352005

• Target :

  STAT

• Related Pathways :

  JAK/STAT Signaling; Stem Cell/Wnt

• Field of Research :

  Cancer

• Smiles :

  O=C1O[C@@H]2[C@H](O3)[C@@]3(C)CC/C=C(CC(F)(F)F)\CC[C@H]2[C@@H]1CN(C)C.OC(/C=C/C(O)=O)=O

• Molecular Formula :

  C22H30F3NO7

• Molecular Weight :

  477.47

• References & Citations :

  [1]Duan X, et al. Discovery of novel fluorine-containing parthenolide analogues as potential antitumor agents. Eur J Med Chem. 2025 Mar 15;286:117283.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  STAT3