BTK-IN-41

• Description:

  BTK-IN-41 (Compound 47) is the inhibitor for BTK with an IC50 of 5.4 nM. BTK-IN-41 inhibits the diffuse large B cell lymphoma cell TDM-8 with IC50 of 13.8 nM[1].

• UNSPSC:

  12352005

• Target:

  Btk

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Smiles:

  O=C (C1=CC=CC (C (F) (F) F) =C1) NC2=CC=C (C) C (NC3=NN (C) C4=C3C=NC (NC5=CC=C6C (C (C) NCC6) =C5) =N4) =C2

• Molecular Formula:

  C31H29F3N8O

• Molecular Weight:

  586.61

• References & Citations:

  [1]KIM P, et al., Pyrazolopyrimidine derivatives, preparation method thereof, and pharmaceutical composition for use in preventing or treating cancer, autoimmune disease and brain disease containing the same as an active ingredient. WO2018208132

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2251799-53-6