Resolvin D3

• Description:

  Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].

• Product Name Alternative:

  RvD3

• UNSPSC:

  12352211

• Hazard Statement:

  H225-H319

• Target:

  AMPK; Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy; Epigenetics; PI3K/Akt/mTOR

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/resolvin-d3.html

• Concentration:

  265.6 μM * 250 μL in Ethanol

• Purity:

  95.0

• Solubility:

  10 mM in DMSO

• Smiles:

  CC/C=C\C[C@H](O)/C=C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCC(O)=O

• Molecular Formula:

  C22H32O5

• Molecular Weight:

  376.49

• Precautions:

  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

• References & Citations:

  [1]Hildur H Arnardottir, et al. Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. J Immunol. 2016 Sep 15;197 (6) :2362-8.|[2]Jennifer K Colby, et al. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Am J Pathol. 2016 Jul;186 (7) :1801-1813.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Solution, -20°C, 2 years

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  916888-47-6