Resolvin D3

• Description :

  Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation[1][2].

• Product Name Alternative :

  RvD3

• UNSPSC :

  12352211

• Hazard Statement :

  H225-H319

• Target :

  AMPK; Autophagy

• Type :

  Reference compound

• Related Pathways :

  Autophagy; Epigenetics; PI3K/Akt/mTOR

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/resolvin-d3.html

• Concentration :

  265.6 μM * 250 μL in Ethanol

• Purity :

  95.0

• Solubility :

  10 mM in DMSO

• Smiles :

  CC/C=C\C[C@H](O)/C=C/C=C\C[C@@H](O)/C=C/C=C/C=C\[C@@H](O)CCC(O)=O

• Molecular Formula :

  C22H32O5

• Molecular Weight :

  376.49

• Precautions :

  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

• References & Citations :

  [1]Hildur H Arnardottir, et al. Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation. J Immunol. 2016 Sep 15;197 (6) :2362-8.|[2]Jennifer K Colby, et al. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Am J Pathol. 2016 Jul;186 (7) :1801-1813.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Solution, -20°C, 2 years

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [916888-47-6]