T-705RMP

• Description:

  T-705RMP, a phosphorylated metabolite of T-705, exhibits a very weak inhibitory effect on the IMP dehydrogenase (IMPDH) activities of the host cells, with an IC50 of 601 μM[1].

• UNSPSC:

  12352005

• Target:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/t-705rmp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COP(O)(O)=O)C=C(F)N=C1C(N)=O

• Molecular Formula:

  C10H13FN3O9P

• Molecular Weight:

  369.20

• References & Citations:

  [1]Furuta Y, et al. Mechanism of action of T-705 against influenza virus. Antimicrob Agents Chemother. 2005;49 (3) :981‐986.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [356783-08-9]