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IKK-IN-3

CAT: 0804-HY-136392Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-136392Size:1 Each
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Description
IKK-IN-3 is a potent and selective IkappaB kinase 2 (IKK2 or IKKβ) inhibitor, with IC50s of 19 and 400 nM for IKK2 and IKK1 (or IKKα), respectively[1].
CAS Number
615528-53-5
UNSPSC
12352005
Target
IKK
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ikk-in-3.html
Solubility
10 mM in DMSO
Smiles
NCCNC1=NC(C=C(C2=CC=CC=C2)S3)=C3N4C1=NC=C4C
Molecular Formula
C17H17N5S
Molecular Weight
323.42
References & Citations
[1]Kempson J , et al. Novel tricyclic inhibitors of IkappaB kinase. J Med Chem. 2009;52 (7) :1994‐2005.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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