IKK-IN-3

• UNSPSC Description:

  IKK-IN-3 is a potent and selective IkappaB kinase 2 (IKK2 or IKKβ) inhibitor, with IC50s of 19 and 400 nM for IKK2 and IKK1 (or IKKα), respectively[1].

• Target Antigen:

  IKK

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ikk-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NCCNC1=NC(C=C(C2=CC=CC=C2)S3)=C3N4C1=NC=C4C

• Molecular Weight:

  323.42

• References & Citations:

  [1]Kempson J , et al. Novel tricyclic inhibitors of IkappaB kinase. J Med Chem. 2009;52(7):1994‐2005.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  615528-53-5