IKK-IN-4

• Description :

  IKK-IN-4 is a potent and selective IkappaB kinase 2 (IKKβ orIKK2) inhibitor, with IC50s of 45 and 650 nM for IKKβ and IKKα, respectively[1].

• UNSPSC :

  12352005

• Target :

  IKK

• Type :

  Reference compound

• Related Pathways :

  NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ikk-in-4.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=CN=C2C(NC)=NC(C=C(C3=CC=CC(CCN)=C3)S4)=C4N21

• Molecular Formula :

  C18H19N5S

• Molecular Weight :

  337.44

• References & Citations :

  [1]Belema M, et al. Synthesis and structure-activity relationship of imidazo (1,2-a) thieno (3,2-e) pyrazines as IKK-beta inhibitors. Bioorg Med Chem Lett. 2007;17 (15) :4284‐4289.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [615529-94-7]