IKK-IN-4

• UNSPSC Description:

  IKK-IN-4 is a potent and selective IkappaB kinase 2 (IKKβ orIKK2) inhibitor, with IC50s of 45 and 650 nM for IKKβ and IKKα, respectively[1].

• Target Antigen:

  IKK

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ikk-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CN=C2C(NC)=NC(C=C(C3=CC=CC(CCN)=C3)S4)=C4N21

• Molecular Weight:

  337.44

• References & Citations:

  [1]Belema M, et al. Synthesis and structure-activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-beta inhibitors. Bioorg Med Chem Lett. 2007;17(15):4284‐4289.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  615529-94-7