(Rac)-3′-Hydroxy simvastatin

(Rac)-3′-Hydroxy simvastatin

• CAS Number: 126313-98-2
• UNSPSC Description: (Rac)-3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].
• Target Antigen: Drug Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/rac-3-hydroxy-simvastatin.html
• Solubility: 10 mM in DMSO
• Smiles: CC(O)C(C)(C)C(OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(O3)=O)C12)=O
• Molecular Weight: 434.57
• References & Citations: [1]Slater, E.E., et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs, 1988. 36 Suppl 3: p. 72-82.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported