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MB-VC-MGBA

CAT: 0804-HY-136289Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-136289Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MB-VC-MGBA is a agent-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC[1].
CAS Number
932744-62-2
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mb-vc-mgba.html
Solubility
10 mM in DMSO
Smiles
ClC[C@H](C1)C(C2=CC=CC=C2C(OC(N(CC3)CCN3C)=O)=C4)=C4N1C(C5=CC6=CC(NC(C(C=C7)=CC=C7NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NCCNC(CCCN(C8=O)C(C=C8)=O)=O)=O)=O)=O)=CC=C6N5)=O
Molecular Formula
C56H65ClN12O10
Molecular Weight
1101.64
References & Citations
[1]Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Duocarmycins

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