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KRAS inhibitor-8

CAT: 0804-HY-135866Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-135866Size:1 Each
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Description
KRAS inhibitor-8 is a potent KRAS G12C inhibitor, extracted from patent WO2017087528A1, compound C[1].
CAS Number
2022986-70-3
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-inhibitor-8.html
Solubility
10 mM in DMSO
Smiles
C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(F)C=CC=C4O)=C(F)C3=NC(OCCN5CC(F)(F)C5)=N2)CC1)=O
Molecular Formula
C26H24ClF4N5O3
Molecular Weight
565.95
References & Citations
[1]Liansheng Li, et al. 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof. WO2017087528A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras

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