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KRAS inhibitor-17

CAT: 0931-T62981-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62981-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2230873-65-9
Target
Ras, Others, Kras
Related Pathways
GPCR/G Protein, Others, MAPK
Bioactivity
KRAS inhibitor-17 (compound 3-9) is a potent inhibitor of KRAS G12C with an IC50 of 3.37 μM. It exhibits p-ERK inhibition with an IC50 of 9.25 μM in MIA PaCA-2 cells and greater than 33.3 μM in A549 cells. KRAS inhibitor-17 has potential applications in the study of pancreatic, colorectal, and lung cancers.
Smiles
FC=1C=2C(=C(SN2)N3CCN(C(C=C)=O)CC3)C=C(Cl)C1C4=CC(OC)=CC=C4Cl
Molecular Formula
C21H18Cl2FN3O2S
Molecular Weight
466.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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GTR19185588-01KRAS inhibitor-17
HY-125875KRAS G12C inhibitor 17
MBS5816601KRAS G12D Inhibitor 17
A18441-10KRAS G12C inhibitor 17 10mg
A18441-5KRAS G12C inhibitor 17 5mg
A18441-1KRAS G12C inhibitor 17 1mg
A18441-100KRAS G12C inhibitor 17 100mg
A18441-50KRAS G12C inhibitor 17 50mg
A18441-25KRAS G12C inhibitor 17 25mg
HY-170785Pan-KRAS-IN-17

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