Carmustine-d8

CAT: 0804-HY-13585SSize: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-13585SSize:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carmustine-d8 is the deuterium labeled Carmustine. Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA[1][2].
Product Name Alternative
BCNU-d8
UNSPSC
12352211
Target
DNA Alkylator/Crosslinker; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Purity
98.34
Solubility
H2O : 100 mg/mL (ultrasonic; warming)
Smiles
[2H]C(Cl)(C([2H])(NC(N(C([2H])(C([2H])(Cl)[2H])[2H])N=O)=O)[2H])[2H]
Molecular Formula
C5HD8Cl2N3O2
Molecular Weight
222.10
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Hung CF. Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells. Neurochem Res. 2000 Jun;25 (6) :845-51.|[3]Demir A, et al. The effect of trimetazidine on intrahepatic cholestasis caused by carmustine in rats. Hepatol Res. 2001 May 1;20 (1) :133-143.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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