Carmustine-d8

• UNSPSC Description:

  Carmustine-d8 is the deuterium labeled Carmustine. Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA[1][2].

• Target Antigen:

  DNA Alkylator/Crosslinker; Isotope-Labeled Compounds

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Cell Cycle/DNA Damage;Others

• Field of Research:

  Cancer

• Purity:

  98.34

• Solubility:

  H2O : 100 mg/mL (ultrasonic;warming)

• Smiles:

  [2H]C(Cl)(C([2H])(NC(N(C([2H])(C([2H])(Cl)[2H])[2H])N=O)=O)[2H])[2H]

• Molecular Weight:

  222.10

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Hung CF. Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells. Neurochem Res. 2000 Jun;25(6):845-51.|[3]Demir A, et al. The effect of trimetazidine on intrahepatic cholestasis caused by carmustine in rats. Hepatol Res. 2001 May 1;20(1):133-143.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  No Development Reported