Carmustine

• Description :

  Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA.

• Product Name Alternative :

  BCNU

• UNSPSC :

  12352211

• Hazard Statement :

  H300, H350, H360

• Target :

  DNA Alkylator/Crosslinker

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Carmustine.html

• Concentration :

  10mM

• Purity :

  99.96

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(NCCCl)N(CCCl)N=O

• Molecular Formula :

  C5H9Cl2N3O2

• Molecular Weight :

  214.05

• Precautions :

  H300, H350, H360

• References & Citations :

  [1]Hung CF. Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells. Neurochem Res. 2000 Jun;25 (6) :845-51.|[2]Demir A, et al. The effect of trimetazidine on intrahepatic cholestasis caused by carmustine in rats. Hepatol Res. 2001 May 1;20 (1) :133-143.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [154-93-8]