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Corticosterone-d8

CAT: 0804-HY-B1618S-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1618S-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
CAS Number
[1271728-07-4]
UNSPSC
12352211
Hazard Statement
H317-H361
Target
Endogenous Metabolite; Glucocorticoid Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Neurological Disease; Endocrinology
Purity
99.91
Solubility
DMSO : ≥ 100 mg/mL|Ethanol : 14.29mg/mL (ultrasonic) |H2O : 0.67mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]3([H])[C@](CC([2H])([2H])C1=C([2H])C(C([2H])([2H])C2)=O)([H])[C@@]4([H])[C@](C[C@@H]3O)([C@@](CC4)([2H])C(C([2H])([2H])O)=O)C
Molecular Formula
C21H22D8O4
Molecular Weight
354.51
Precautions
P261-P272-P280-P302+P352-P362+P364-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Gasser PJ, et al. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organiccation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci. 2006 Aug 23;26 (34) :8758-8766.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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