Corticosterone-d8

• Description :

  Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.

• CAS Number :

  [1271728-07-4]

• UNSPSC :

  12352211

• Hazard Statement :

  H317-H361

• Target :

  Endogenous Metabolite; Glucocorticoid Receptor; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Neurological Disease; Endocrinology

• Purity :

  99.91

• Solubility :

  DMSO : ≥ 100 mg/mL|Ethanol : 14.29mg/mL (ultrasonic) |H2O : 0.67mg/mL (ultrasonic)

• Smiles :

  C[C@@]12[C@]3([H])[C@](CC([2H])([2H])C1=C([2H])C(C([2H])([2H])C2)=O)([H])[C@@]4([H])[C@](C[C@@H]3O)([C@@](CC4)([2H])C(C([2H])([2H])O)=O)C

• Molecular Formula :

  C21H22D8O4

• Molecular Weight :

  354.51

• Precautions :

  P261-P272-P280-P302+P352-P362+P364-P405-P501

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Gasser PJ, et al. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organiccation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci. 2006 Aug 23;26 (34) :8758-8766.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported