Corticosterone-d8

Corticosterone-d8

• CAS Number: 1271728-07-4
• UNSPSC Description: Corticosterone-d8 is the deuterium labeled Corticosterone. Corticosterone is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
• Target Antigen: Endogenous Metabolite; Glucocorticoid Receptor; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;Others;Vitamin D Related/Nuclear Receptor
• Field of Research: Neurological Disease; Endocrinology
• Purity: 99.91
• Solubility: DMSO : ≥ 100 mg/mL
• Smiles: C[C@@]12[C@]3([H])[C@](CC([2H])([2H])C1=C([2H])C(C([2H])([2H])C2)=O)([H])[C@@]4([H])[C@](C[C@@H]3O)([C@@](CC4)([2H])C(C([2H])([2H])O)=O)C
• Molecular Weight: 354.51
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Gasser PJ, et al. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organiccation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci. 2006 Aug 23;26(34):8758-8766.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported