Products for Research Use Only
RegisterLogin

HDHODH-IN-5

CAT: 0804-HY-135664Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-135664Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DHODH-IN-7 is a human dihydroorotate dehydrogenase (DHODH) inhibitor, with an IC50 of 0.91 μM. DHODH-IN-7 induces differentiation in acute myeloid leukemia[1].
CAS Number
2029049-77-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhodh-in-7.html
Purity
98.55
Solubility
10 mM in DMSO
Smiles
O=C(NCCC(N[C@@H]1CCCC2=C1C=CC=C2)=O)C3=CC=C(C(F)(F)F)C=C3
Molecular Formula
C21H21F3N2O2
Molecular Weight
390.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016 Sep 28;7 (12) :1112-1117.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-157153HDHODH-IN-14
HY-135654HDHODH-IN-2
HY-145261HDHODH-IN-8
HY-135658-01HDHODH-IN-1
HY-135570-01HDHODH-IN-3
HY-151381HDHODH-IN-10
HY-135667HDHODH-IN-7
HY-159119HDHODH-IN-15
HY-149642-01HDHODH-IN-13
HY-173354HDHODH-IN-17

Alternative Products

CatalogName
GTR19176806-01HDHODH-IN-5
BA7298-5hDHODH-IN-13
BA4054-10hDHODH-IN-1
T88973-01HDHODH-IN-15
T11025-01HDHODH-IN-3
T63238-01hDHODH-IN-8
T11031-01HDHODH-IN-7
MBS5815189hDHODH-IN-11
BUP16207-01HDHODH-IN-4
MBS5805712hDHODH-IN-10

Popular Products