Products for Research Use Only
RegisterLogin

ABT-510

CAT: 0804-HY-13545-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-13545-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ABT-510 is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer. ABT-510 also reduces angiogenesis and inflammatory responses in a murine model of inflammatory bowel disease. ABT-510 can be used in studies of cancer (particularly epithelial ovarian cancer) and inflammatory bowel disease (IBD) [1][2].
CAS Number
251579-55-2
UNSPSC
12352209
Hazard Statement
H302-H315-H319
Target
Apoptosis
Type
Peptides
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/abt-510.html
Purity
99.87
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC(N(C)CC(NCC(N[C@@H](C(C)C)C(N[C@H]([C@@H](C)CC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(NCC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C46H83N13O11
Molecular Weight
994.23
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Greenaway J, et al. ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer. Mol Cancer Ther. 2009 Jan;8 (1) :64-74.|[2]Punekar S, et al. Thrombospondin 1 and its mimetic peptide ABT-510 decrease angiogenesis and inflammation in a murine model of inflammatory bowel disease. Pathobiology. 2008;75 (1) :9-21. |[3]Isenberg JS, et.al. Differential effects of ABT-510 and a CD36-binding peptide derived from the type 1 repeats of thrombospondin-1 on fatty acid uptake, nitric oxide signaling, and caspase activation in vascular cells. Biochem Pharmacol. 2008 Feb 15;75 (4) :875-82.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 2

Related Products

CatalogName
HY-101634-01ABT-072
HY-175283ABT-002
HY-19483ABT-670
HY-125309ABT-299
HY-15197-01ABT-046
HY-115133ABT-116
HY-120232-01ABT-963
HY-12195-01ABT-239
HY-19721-01ABT-639
HY-50907-01ABT-737

Alternative Products

CatalogName
MBS5812146ABT-510
BUP01039-01ABT-510 acetate
B7737-50ABT
B8399-5AMG 510
B2558-5AMG-510
MBS387176-01ANX-510
ABL-TC0153Detroit 510
OR1078653-01Coumarin 510
ARC0425KYSE-510
466257SCOTfluor-510

Popular Products