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IDO1-IN-7

CAT: 0804-HY-134583Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-134583Size:1 Each
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Description
IDO1-IN-7 is a highly potent and selective indoleamine-2,3-dioxygenase-1 (IDO1) inhibitor, with an IC50 of 6.1 nM in in the cellular assay (SKOV3) . IDO1-IN-7 has immunomodulatory effects. IDO1-IN-7 can be used for the research of cancer[1].
CAS Number
2351199-98-7
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-in-7.html
Solubility
10 mM in DMSO
Smiles
FC1=CC2=C(C=C1)N=CC=C2[C@@H](CC3)[C@@H](O)CN3C(C(NC4=CC=C(Cl)C=C4)=O)=O
Molecular Formula
C22H19ClFN3O3
Molecular Weight
427.86
References & Citations
[1]Christoph Steeneck, et al. Discovery and optimization of substituted oxalamides as novel heme-displacing IDO1 inhibitors. Bioorg Med Chem Lett. 2020 Dec 15;33:127744.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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