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IDO1-IN-14

CAT: 0804-HY-144274Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144274Size:1 Each
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Description
IDO1-IN-14 (compound 4a) is a potent IDO1 inhibitor with an IC50 of 396.9 nM. IDO1-IN-14 has cellular IDO1 inhibition (HeLa EC50=3393 nM) [1].
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-in-14.html
Solubility
10 mM in DMSO
Smiles
O/N=C(C1=CN=C(C=C1)OC2=CC(Cl)=CC=C2)/NC3=CC=C(C(Cl)=C3)F
Molecular Formula
C18H12Cl2FN3O2
Molecular Weight
392.21
References & Citations
[1]Yeh TK, et al. Discovery and development of a novel N- (3-bromophenyl) -{[ (phenylcarbamoyl) amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design. Eur J Med Chem. 2022;229:114043.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1

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