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Bis-BCN-PEG1-diamide

CAT: 0804-HY-133510Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-133510Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bis-BCN-PEG1-diamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-BCN-PEG1-diamide is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-bcn-peg1-diamide.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCNC(COCC1C2C1CCC#CCC2)=O)COCC3C4CCC#CCCC43
Molecular Formula
C28H40N2O5
Molecular Weight
484.63
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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