Bis-PEG12-endo-BCN

Bis-PEG12-endo-BCN

• UNSPSC Description: Bis-PEG12-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-PEG12-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/bis-peg12-endo-bcn.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(OCC1C2CCC#CCCC12)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC3C4CCC#CCCC34)=O
• Molecular Weight: 941.15
• References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported