DNMT-IN-1

• UNSPSC Description:

  DNMT-IN-1 is a potent DNMT inhibitor with an EC50 value of 3.2 µM. DNMT-IN-1 shows antiproliferative active[1].

• Target Antigen:

  DNA Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dnmt-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  Br[C@@]1([N+]([O-])=O)[C@@H](C2=C([N+]([O-])=O)C=CC=C2)OC3=CC=CC=C3C1=O

• Molecular Weight:

  393.15

• References & Citations:

  [1]Pechalrieu D, et al. Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells. Eur J Med Chem. 2020 Jan 15;186:111829.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2396691-28-2