DNMT-IN-1

DNMT-IN-1

• CAS Number: 2396691-28-2
• UNSPSC Description: DNMT-IN-1 is a potent DNMT inhibitor with an EC50 value of 3.2 µM. DNMT-IN-1 shows antiproliferative active[1].
• Target Antigen: DNA Methyltransferase
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dnmt-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: Br[C@@]1([N+]([O-])=O)[C@@H](C2=C([N+]([O-])=O)C=CC=C2)OC3=CC=CC=C3C1=O
• Molecular Weight: 393.15
• References & Citations: [1]Pechalrieu D, et al. Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells. Eur J Med Chem. 2020 Jan 15;186:111829.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported