DNMT-IN-3

• UNSPSC Description:

  DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC50 of 60 nM against Plasmodium falciparum (Plasmodium). DNMT-IN-3 can be used for malaria related research[1].

• Target Antigen:

  DNA Methyltransferase; Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Epigenetics

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dnmt-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C1(NCCNC2=CC=CC3=C2C=CC=C3)=C4C=CC(OCC5CCN(CC5)CCNC6=C7C=CC=CC7=NC=C6)=CC4=NC=N1

• Molecular Weight:

  597.75

• References & Citations:

  [1]Dobrescu I, et.al. Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors. ACS Infect Dis. 2023 Jun 9; 9(6):1257-1266.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1683516-27-9