DNMT-IN-3

DNMT-IN-3

• CAS Number: 1683516-27-9
• UNSPSC Description: DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC50 of 60 nM against Plasmodium falciparum (Plasmodium). DNMT-IN-3 can be used for malaria related research[1].
• Target Antigen: DNA Methyltransferase; Parasite
• Type: Reference compound
• Related Pathways: Anti-infection;Epigenetics
• Applications: COVID-19-immunoregulation
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/dnmt-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: C1(NCCNC2=CC=CC3=C2C=CC=C3)=C4C=CC(OCC5CCN(CC5)CCNC6=C7C=CC=CC7=NC=C6)=CC4=NC=N1
• Molecular Weight: 597.75
• References & Citations: [1]Dobrescu I, et.al. Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors. ACS Infect Dis. 2023 Jun 9; 9(6):1257-1266.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported