Products for Research Use Only

DNMT-IN-5

CAT: 0931-T211294-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211294-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
DNA Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
DNMT-IN-5 is a potent and stable inhibitor of DNA methyltransferase (DNMT), with an IC50 of 0.78 nM. It exhibits submicromolar inhibitory activity against DNMT3A, upregulates the expression of target genes, inhibits cell proliferation, and induces key cell cycle arrest. DNMT-IN-5 is suitable for research on p53-deficient colorectal cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C