CFT-2718

• UNSPSC Description:

  CFT-2718 is a new BRD4-targeting degrader (PROTAC) with enhanced catalytic activity and in vivo properties.

• Target Antigen:

  PROTACs

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cft-2718.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(CC2=C(C=CC=C21)N[C@@H]3CCN(C3)CCCCCCN4N=CC(C5=CC6=C(C=C5)N7C(C)=NN=C7C8(CC8)N=C6C9=CC=C(C=C9)Cl)=C4)C%10C(NC(CC%10)=O)=O

• Molecular Weight:

  811.37

• References & Citations:

  [1]Sun D, et al. Evaluation of the Small-molecule BRD4 Degrader CFT-2718 in Small-cell Lung Cancer and Pancreatic Cancer Models. Mol Cancer Ther. 2021 Aug;20(8):1367-1377.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported