CFT-1297

• UNSPSC Description:

  CFT-1297 is a BET PROTAC degrader that can degrade BRD4[1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cft-1297.html

• Smiles:

  CC1=NN=C2N1C3=C(C(C4=CC=C(C=C4)O)=NC25CC5)C=C(C=C3)C6=CN(N=C6)CCCCCCCN7CCC(CC7)C8=CC=CC9=C8CN(C9=O)C%10CCC(NC%10=O)=O

• Molecular Weight:

  805.97

• References & Citations:

  [1]Kroupova A, et, al. Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders. Nat Commun. 2024 Oct 15;15(1):8885.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported