CFT-1297

• Description :

  CFT-1297 is a BET PROTAC degrader that can degrade BRD4[1].

• CAS Number :

  [2154353-03-2]

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain; PROTACs

• Type :

  Reference compound

• Related Pathways :

  Epigenetics; PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cft-1297.html

• Smiles :

  CC1=NN=C2N1C3=C(C(C4=CC=C(C=C4)Cl)=NC25CC5)C=C(C=C3)C6=CN(N=C6)CCCCCCCN7CCC(CC7)C8=CC=CC9=C8CN(C9=O)C%10CCC(NC%10=O)=O

• Molecular Formula :

  C47H50ClN9O3

• Molecular Weight :

  824.41

• References & Citations :

  [1]Kroupova A, et, al. Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders. Nat Commun. 2024 Oct 15;15 (1) :8885.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported