Cidofovir diphosphate

Cidofovir diphosphate

• CAS Number: 142276-31-1
• UNSPSC Description: Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively[1][2].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/cidofovir-diphosphate.html
• Solubility: 10 mM in DMSO
• Smiles: O=P(O)(O)OP(OP(CO[C@H](CO)CN1C(N=C(C=C1)N)=O)(O)=O)(O)=O
• Molecular Weight: 439.15
• References & Citations: [1]Hitchcock MJM, et al. Cidofovir, a New Agent with Potent Anti-Herpesvirus Activity. 1996. |[2]Magee WC, et al. Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate. Antimicrob Agents Chemother. 2005 Aug;49(8):3153-62.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported