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Cidofovir diphosphate

CAT: 0804-HY-131606Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-131606Size:1 Each
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Description
Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively[1][2].
CAS Number
142276-31-1
UNSPSC
12352005
Target
CMV; HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cidofovir-diphosphate.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(O)OP(OP(CO[C@H](CO)CN1C(N=C(C=C1)N)=O)(O)=O)(O)=O
Molecular Formula
C8H16N3O12P3
Molecular Weight
439.15
References & Citations
[1]Hitchcock MJM, et al. Cidofovir, a New Agent with Potent Anti-Herpesvirus Activity. 1996. |[2]Magee WC, et al. Mechanism of inhibition of vaccinia virus DNA polymerase by cidofovir diphosphate. Antimicrob Agents Chemother. 2005 Aug;49 (8) :3153-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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