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Cabergoline (diphosphate)

CAT: 0804-HY-15296ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-15296ASize:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cabergoline diphosphate is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively) .
CAS Number
[85329-89-1]
Product Name Alternative
FCE-21336 (diphosphate)
UNSPSC
12352005
Target
Autophagy; Dopamine Receptor
Type
Reference compound
Related Pathways
Autophagy; GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/cabergoline-diphosphate.html
Smiles
O=P(O)(O)O.C=CCN1[C@@]2([H])[C@@](C[C@H](C1)C(N(CCCN(C)C)C(NCC)=O)=O)([H])C3=CC=CC4=C3C(C2)=CN4.O=P(O)(O)O
Molecular Formula
C26H43N5O10P2
Molecular Weight
647.59
References & Citations
[1]Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9 (6) :e99271.|[2]Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155 (11) :4411-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor

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