Cabergoline (diphosphate)

• Description :

  Cabergoline diphosphate is an ergot derived-dopamine D2-like receptor agonist that has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively) .

• Product Name Alternative :

  FCE-21336 (diphosphate)

• UNSPSC :

  12352005

• Target :

  Autophagy; Dopamine Receptor

• Type :

  Reference compound

• Related Pathways :

  Autophagy; GPCR/G Protein; Neuronal Signaling

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cabergoline-diphosphate.html

• Smiles :

  O=P(O)(O)O.C=CCN1[C@@]2([H])[C@@](C[C@H](C1)C(N(CCCN(C)C)C(NCC)=O)=O)([H])C3=CC=CC4=C3C(C2)=CN4.O=P(O)(O)O

• Molecular Formula :

  C26H43N5O10P2

• Molecular Weight :

  647.59

• References & Citations :

  [1]Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9 (6) :e99271.|[2]Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155 (11) :4411-21.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT2 Receptor

• CAS Number :

  [85329-89-1]