Cdc7-IN-4

• Description :

  Cdc7-IN-4 (compound I-C) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-C. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle[1].

• CAS Number :

  [1402059-21-5]

• UNSPSC :

  12352005

• Target :

  CDK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/cdc7-in-4.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C(C/1=O)=C(NN2CCN(CC(F)(F)F)CC2)OC1=C/C3=CNC4=NC=CC=C43)OC(C)C

• Molecular Formula :

  C22H24F3N5O4

• Molecular Weight :

  479.45

• References & Citations :

  [1]Christian Andrew HASSIG, et al. Methods of treatment of cancer comprising cdc7 inhibitors. WO2019165473A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported