Cdc7-IN-4

CAT: 0804-HY-130516Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-130516Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cdc7-IN-4 (compound I-C) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-C. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle[1].
CAS Number
[1402059-21-5]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdc7-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C/1=O)=C(NN2CCN(CC(F)(F)F)CC2)OC1=C/C3=CNC4=NC=CC=C43)OC(C)C
Molecular Formula
C22H24F3N5O4
Molecular Weight
479.45
References & Citations
[1]Christian Andrew HASSIG, et al. Methods of treatment of cancer comprising cdc7 inhibitors. WO2019165473A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported