TT-OAD2 (free base)

TT-OAD2 (free base)

• CAS Number: 1246826-07-2
• UNSPSC Description: TT-OAD2 free base is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC50 of 5 nM. TT-OAD2 free base has the potential for diabetes treatment[1][2].
• Target Antigen: GCGR
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/glp-1-receptor-agonist-5.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)[C@H](CC1=CC=C(C2=C(C)C(C)=NC=C2)C=C1)NC([C@H]3N([C@H](C4=CC=CC=C4)CC)CC5=C(C=C(OC[C@H](C6=CC=C(OCC7=CC=C(Cl)C(Cl)=C7)C=C6)O8)C8=C5)C3)=O
• Molecular Weight: 856.83
• References & Citations: [1]Transtech Pharma, et al. Substituted azoanthracene derivatives, pharmaceutical compositions, and methods of use thereof. WO2010114824A1.|[2]Zhao P, et al. Activation of the GLP-1 receptor by a non-peptidic agonist. Nature. 2020 Jan;577(7790):432-436.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported