CCTA-1523

• Description:

  CCTA-1523 is a potent, selective, reversible and orally active ABCG2 inhibitor. CCTA-1523 shows cytotoxicity. CCTA-1523 shows anticancer activity[1].

• UNSPSC:

  12352005

• Target:

  BCRP

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ccta-1523.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C(Cl)Cl)NC1=CC(C2=CC=C(C(OC)=C2)OC)=CC=C1

• Molecular Formula:

  C16H15Cl2NO3

• Molecular Weight:

  340.20

• References & Citations:

  [1]Patel A, et al. Suppression of ABCG2 mediated MDR in vitro and in vivo by a novel inhibitor of ABCG2 drug transport. Pharmacol Res. 2017 Jul;121:184-193.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1616271-41-0]