USP7-IN-6

• Description:

  USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor, extracted from patent WO2017212010A1, example 25, has an IC50 of 6.8 nM[1].

• UNSPSC:

  12352005

• Target:

  Deubiquitinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/usp7-in-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(N(C3=CC=C(CO)C=C3)C=C2)N=CN1CC4(O)CCN(C([C@H]5[C@H](C6=CC=CC=C6)CN(CC7=CN=C(C8=CC=C(C)N=C8)S7)CC5)=O)CC4

• Molecular Formula:

  C41H43N7O4S

• Molecular Weight:

  729.89

• References & Citations:

  [1]András Kotschy, et al. New (hetero) aryl-substituted-piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them. WO2017212010A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2166586-47-4]