SP-Chymostatin B

• Description:

  SP-Chymostatin B (α-MAPI) is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A, B, C, H, and L. SP-Chymostatin B weakly inhibits human leucocyte elastase[1].

• Product Name Alternative:

  α-MAPI

• UNSPSC:

  12352005

• Target:

  Elastase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/sp-chymostatin-b.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)[C@H](CC1=CC=CC=C1)NC(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](C=O)CC2=CC=CC=C2)=O)=O)=O

• Molecular Formula:

  C30H41N7O6

• Molecular Weight:

  595.69

• References & Citations:

  [1]Syuichi Oka, et al. Protease Inhibitors Produced by Streptomyces libani. Agricultural and Biological Chemistry, Volume 43, Issue 4, 1 April 1979, Pages 691–696

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [70857-49-7]