LC-PEG8-SPDP

• UNSPSC Description:

  LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

• Target Antigen:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/lc-peg8-spdp.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCSSC2=NC=CC=C2)=O

• Molecular Weight:

  735.86

• References & Citations:

  [1]Zhao RY, et al. Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates. J Med Chem. 2011 May 26;54(10):3606-23.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1252257-56-9