SPDP-PEG4-NHS ester

• Description:

  SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/spdp-peg4-nhs-ester.html

• Purity:

  98.0

• Solubility:

  H2O : 5 mg/mL (ultrasonic)

• Smiles:

  O=C (ON1C (CCC1=O) =O) CCOCCOCCOCCOCCNC (CCSSC2=NC=CC=C2) =O

• Molecular Formula:

  C23H33N3O9S2

• Molecular Weight:

  559.65

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl/ether Linkers; PEG Linkers

• CAS Number:

  1334177-95-5