RAF mutant-IN-1
CAT:
804-HY-126298
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RAF mutant-IN-1
- CAS Number: 2340020-82-6
- UNSPSC Description: RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
- Target Antigen: Raf
- Type: Reference compound
- Related Pathways: MAPK/ERK Pathway
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/raf-mutant-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(O)C(Cl)=C5F.[H]Cl.[H]Cl
- Molecular Weight: 567.85
- References & Citations: [1]BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported